Without the appropriate inhibitors and/or operating environment, ethylene glycol can 'break-down' to form acids (see below). These acids will greatly accelerate corrosion within multi-metal heating and cooling systems.

Propylene glycol undergoes metabolic oxidation to pyruvic acid, acetic acid, lactic acid, and propionaldehyde (Miller & Bazzano, 1965; Ruddick, 1972).

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